Sample Size for Paired Cohort Studies

 

Menu location: Analysis_Sample Size_Paired Cohort.

 

This function gives you the minimum number of subject pairs that you require to detect a true relative risk RR with power POWER and two sided type I error probability ALPHA (Dupont, 1990; Breslow and Day, 1980).

 

Information required

 

Practical issues

 

Technical validation

The estimated sample size n is calculated as:

- where α = alpha, β = 1 - power and zp is the standard normal deviate for probability p. n is rounded up to the closest integer.

 

 

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